Machine learning on alignment features for parent-of-origin classification of simulated hybrid RNA-seq
Abstract Background Parent-of-origin allele-specific gene expression (ASE) can be detected in interspecies hybrids by virtue bostik roll-cote of RNA sequence variants between the parental haplotypes.ASE is detectable by differential expression analysis (DEA) applied to the counts of RNA-seq read pairs aligned to parental references, but aligners do